Kev Siv Tshuab Kho Molecular Hloov Pauv Txoj Kev Ua Haujlwm Ib Xyoos Dhau Los, Kev Siv Tshuab Aromatic Amine Direct Deamination Ua Rau Kev Hloov Pauv ntawm Cov Khoom Siv Industrial Chain

Kev Tshawb Fawb Tseem Ceeb

Thaum Lub Kaum Hli Ntuj hnub tim 28, cov thev naus laus zis ua haujlwm ncaj qha rau cov amines aromatic uas Zhang Xiaheng pab pawg los ntawm Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences (HIAS, UCAS) tau luam tawm hauv Nature. Cov thev naus laus zis no daws cov teeb meem kev nyab xeeb thiab tus nqi uas tau ua rau kev lag luam tshuaj lom neeg muaj teeb meem rau 140 xyoo.

Cov Ntsiab Lus Tseem Ceeb

1. Tso tseg cov txheej txheem ntsev diazonium ib txwm muaj (feem ntau yuav tawg thiab muaj kuab paug ntau), ua tiav kev hloov pauv CN bond zoo los ntawm N-nitroamine intermediates.
2. Tsis tas yuav siv cov tshuaj catalysts hlau, txo cov nqi tsim khoom los ntawm 40% -50%, thiab tau ua tiav kev txheeb xyuas qhov ntsuas kilogram.
3. Siv tau rau yuav luag txhua yam tshuaj heteroaromatic amines thiab aniline derivatives, yam tsis raug txwv los ntawm txoj haujlwm ntawm pawg amino.

Kev Cuam Tshuam Hauv Kev Lag Luam

1. Kev lag luam tshuaj: Raws li lub cev tseem ceeb ntawm 70% ntawm cov tshuaj me me, kev tsim cov tshuaj nruab nrab rau cov tshuaj tiv thaiv kab mob qog noj ntshav thiab cov tshuaj tiv thaiv kev ntxhov siab ua rau muaj kev nyab xeeb dua thiab pheej yig dua. Cov lag luam zoo li Baicheng Pharmaceutical xav tias yuav pom kev txo nqi 40% -50%.
2. Kev lag luam xim: Cov tuam txhab ua lag luam xws li Zhejiang Longsheng, uas tuav 25% feem ntawm kev ua lag luam hauv cov tshuaj amines, daws qhov kev pheej hmoo tawg uas tau txwv tsis pub muaj peev xwm nthuav dav ntev.
3. Kev lag luam tshuaj tua kab: Cov lag luam suav nrog Yangnong Chemical yuav muaj kev txo qis ntawm cov nqi ntawm cov tshuaj tua kab nruab nrab.
4. Cov ntaub ntawv hluav taws xob: Txhawb nqa kev tsim cov khoom siv tshwj xeeb.

Kev Lag Luam Peev Xwm Teb Chaws

Thaum Lub Kaum Ib Hlis 3, cov khoom siv tshuaj lom neeg tau muaj zog tiv thaiv kev lag luam, nrog rau cov khoom siv aromatic amine ua tus thawj coj ntawm cov txiaj ntsig thiab cov khoom lag luam cuam tshuam qhia txog kev muaj zog tag nrho.