Molecular Editing Technology Revolutionizes Century-old Process, Aromatic Amine Direct Deamination Technology Triggers Industrial Chain Transformation

Core Breakthrough

Thaum Lub Kaum Hli 28, qhov ncaj qha deamination functionalization tshuab rau aromatic amines tsim los ntawm Zhang Xiaheng pab neeg los ntawm Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences (HIAS, UCAS) tau luam tawm hauv Xwm. Cov thev naus laus zis no daws cov teeb meem kev nyab xeeb thiab nqi uas tau ua rau muaj kev lag luam tshuaj lom neeg rau 140 xyoo.

Technical Highlights

1.Tshaj tawm cov txheej txheem diazonium ntsev (nruab nrab rau kev tawg thiab muaj kuab paug siab), ua tiav CN daim ntawv cog lus hloov pauv los ntawm N-nitroamine intermediates.
2.Yuav tsum tsis muaj hlau catalysts, txo cov nqi tsim khoom los ntawm 40% -50%, thiab tau ua tiav cov ntawv pov thawj kilogram.
3.Ua tau rau yuav luag txhua cov tshuaj heteroaromatic amines thiab aniline derivatives, tsis muaj kev txwv los ntawm txoj hauj lwm ntawm pawg amino.

Muaj kev cuam tshuam

1. Pharmaceutical kev lag luam: Raws li lub pob txha tseem ceeb ntawm 70% ntawm cov tshuaj me me, kev sib txuas ntawm intermediates rau cov tshuaj tiv thaiv kab mob thiab cov tshuaj tiv thaiv kev ntxhov siab yuav muaj kev nyab xeeb thiab kev lag luam ntau dua. Cov lag luam xws li Baicheng Pharmaceutical yuav tsum pom qhov txo nqi 40% -50%.
2.Dyestuff kev lag luam: Cov tuam txhab ua lag luam xws li Zhejiang Longsheng, uas tuav 25% kev ua lag luam sib koom hauv cov tshuaj tsw qab amines, daws qhov kev pheej hmoo tawg uas tau txwv ntev kev nthuav dav.
3. Kev lag luam tshuaj tua kab: Cov lag luam suav nrog Yangnong Tshuaj yuav muaj kev txo nqi ntawm cov tshuaj tua kab nruab nrab.
4. Cov khoom siv hluav taws xob: Txhawb kev sib xyaw ntsuab ntawm cov khoom siv tshwj xeeb.

Capital Market Reaction

Thaum Lub Kaum Ib Hlis 3, cov khoom siv tshuaj lom neeg muaj zog tiv thaiv kev ua lag luam, nrog rau ntu amine uas ua rau muaj txiaj ntsig thiab muaj feem cuam tshuam cov tswv yim cov khoom lag luam uas qhia txog qhov tseem ceeb.